Accelerated Whole Genome Sequencing Analysis

Experience high-throughput, high-accuracy DNA and RNA sequencing with NVIDIA Clara Parabricks.

Free 90-Day Trial

Power faster, more accurate genomic analysis with NVIDIA Clara™ Parabricks. A GPU-accelerated computational genomics application framework, Clara Parabricks delivers accurate and accelerated analysis of next-generation sequencing data for researchers and clinical teams, as well as medical and sequencing centers for genetic diseases and cancer.

View Document: Parabricks Product Sheet (PDF 304 kB)
High Throughput

High Throughput

Process up to 60 whole genomes per day on a single server.

Better Accuracy

Better Accuracy

No need to sacrifice accuracy to reduce turnaround time. A suite of germline and somatic callers is available.

Flexible Pipelines

Flexible Pipelines

Create customized, accelerated pipelines by configuring over 33 tools for any specific pipeline or application need.

30–60X Faster

30–60X Faster

Reduce computing costs up to 50 percent by running 30–60X faster than CPU-only solutions.

Bringing GPU-Accelerated Performance to Bioinformatics

Accelerate end-to-end pipelines, from FastQ to Variant Call Format (VCF), in as little as 23 minutes for a whole genome and three minutes for a whole exome.

Data was generated using publicly available data for NA 12878 deprecating the data to 30x coverage. For the 23 minute run time, DGX A100 with 320G memory was used. The native GATK4.1 numbers were generated using 32 vCPU [3.1 GHz Intel Xeon® Platinum 8175M] using 128 Gb RAM.

Getting Around Faster and Easier

REDCINE-X PRO performance measures geomean FPS of 6K and 8K video.

Accelerated Applications for Genomic Analysis

From FASTQ to Binary Alignment Map (BAM) to VCF, NVIDIA accelerates genomics analysis for somatic, germline and structural variant workflows, as well as improving sequencer speeds and consensus read base calling accuracy.

FASTQ to Binary Alignment Map (BAM) to VCF

Next-Generation Sequencing on Premise or in the Cloud

Running NVIDIA Clara Parabricks requires a minimum of two GPUs. On-premise licenses are annual subscriptions on a per-GPU basis, which include full access to all pipelines in the NVIDIA Clara Parabricks software suite.

NVIDIA DGX A100

On-Premise Solutions

Running on one NVIDIA DGX™ A100, Clara Parabricks analyzes up to 25,000 whole genomes per year (30X coverage) with Genomic Analysis Toolkit (GATK) from Broad Institute. Throughput scales linearly beyond a single DGX A100.

Learn more about DGX A100

In the Cloud

In the cloud, time is money. Choose from a range of GPU instances capable of analyzing genomes in a matter of minutes. For easy deployment on AWS has Clara Parabricks available in an Amazon Machine Image (AMI) for immediate use.

Explore the AWS Marketplace
AWS Marketplace : NVIDIA Clara Parabricks Pipelines

How Clara Parabricks Is Making a Real-World Impact

DeepVariant with Clara Parabricks

Regeneron Genetics Center

See how Regeneron is using DeepVariant with Clara Parabricks to generate scalable, high-quality data that can be reproduced across the genomics community.

Watch webinar
NVIDIA DGX A100 and Clara Parabricks

National Biobank of Thailand (NBT)

NBT reduced its whole genome sequencing data processing by four months and its individual user processing time from over 30 hours to just 1-2 hours with NVIDIA DGX A100 and Clara Parabricks.

Read article
NVIDIA V100 Tensor Core GPUs

Translational Genomics Research Institute (TGen)

With NVIDIA Clara Parabricks and NVIDIA V100 Tensor Core GPUs, TGen sped up genomic sequencing analysis by 6X to help determine personalized treatments for children with rare neurological disorders.

Read success story
NVIDIA Clara Parabricks

Washington University in Saint Louis (WUSTL)

Integrating GPU-based steps with NVIDIA Clara Parabricks enabled Tychele Turner of WUSTL to drastically reduce the runtime for de novo variant calling.

Watch webinar

Resources

  • Enterprise Support
  • Documentation

Parabricks Pipelines Support Services provides you with an easy, reliable way to improve productivity and reduce system downtime for your production analysis systems. NVIDIA Support Services for Parabricks includes:

  • Direct communication with NVIDIA technical and domain experts
  • Help with installation and usage of Parabricks Pipelines
  • Rapid response and timely issue resolution (cases are accepted for 24/7 remote support)
  • Access to all software upgrades, maintenance releases, bug fixes, and security patches
  • Help with temporary workarounds for confirmed bugs

Get Started Today

Already have an active support contract?

Log into the support portal >

Want to renew your contract?

Contact your sales rep.

Any additional questions?

Contact parabricks-support@nvidia.com

Getting Started

Clara Parabricks can be set up in just 10 minutes with a 90-day free trial. Watch a short video for a step-by-step walkthrough or learn more about the software suite and tools available in the Parabricks technical documentation.

Start a free 90-day trial of NVIDIA Clara Parabricks today or contact our sales team to get a quote.

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